Weight loss, otherwise known as fat loss, becomes progressively more difficult as we age, not because of a lack of effort, but because of how declining hormones reshape our metabolism. Declining growth hormone, accumulating metabolic resistance, and changes in insulin sensitivity all contribute to a body composition that increasingly resists the approaches that worked in younger years. At SkinMD in Greater Boston, peptide therapy addresses fat loss from the metabolic and hormonal root, not through appetite suppression alone, but through restoring the physiological conditions in which your body efficiently burns fat.
What Causes Weight Loss?
Fat accumulation in adults is often driven by declining growth hormone (which reduces lipolysis, the process of burning stored fat), insulin resistance, hormonal imbalances, poor sleep (which elevates cortisol and disrupts fat metabolism), and metabolic inefficiency. Dieting alone cannot fix these physiological shifts and can often make them worse through muscle loss, metabolic adaptation, and nutrient depletion.
Signs You May Be Experiencing This
- Increasing difficulty losing fat despite diet and exercise
- Body fat accumulation particularly around the abdomen, flanks, and hips
- History of yo-yo dieting with diminishing returns
- Weight loss with GLP-1 medications but lingering body fat in stubborn areas
- Loss of muscle tone alongside fat gain
- Metabolic markers trending in the wrong direction
How Peptide Therapy Can Help
Sermorelin directly enhances lipolysis, your body’s fat-burning pathway, through natural growth hormone stimulation. NAD+ supports the metabolic machinery that makes fat-burning efficient at the cellular level. For GLP-1 patients, peptides are powerful complements: they preserve muscle during caloric restriction and enhance metabolic efficiency. SkinMD coordinates these protocols with any existing weight management program.
Recommended Peptide Treatments
Based on your symptoms, health history, and lab results, your SkinMD provider may recommend one or more of the following:
Sermorelin
Supports GH-driven metabolism and body composition change. GH directly stimulates lipolysis, facilitating fat loss, especially when combined with exercise.
NAD+
Improves mitochondrial efficiency, ensuring your metabolic machinery is running optimally to support fat burning.
B12 Injections
Addresses B12 deficiency that can contribute to metabolic sluggishness and reduced energy for physical activity.
our team
At SkinMD, we prioritize a physician-led approach to beauty. Our founder and medical director, Dr. Paul Flashner, ensures that our master injectors and aestheticians are trained in the latest techniques under his expert guidance. We leverage cutting-edge technologies to enhance your natural beauty while delivering exceptional results. The trust we cultivate with our patients through consistent, natural outcomes is what truly brings us joy.
MEET THE TEAM
Skin MD has a beautiful atmosphere, friendly staff, affordable pricing, and any treatment your skin needs. I received the Venus Legacy treatment (a collagen-boosting treatment) from Shannon and had a wonderful experience. Not only was it like a warm massage for my face, but this treatment gave IMMEDIATE plumping, increased blood circulation, and made my skin glow! I will definitely be coming back for all my skin needs and medical-grade skin care. I recommend it to everyone!
~ Skyla M.
The staff are so welcoming and comforting. They take time to listen to your needs and they do not pressure you into doing anything you don't want to do. They also take time to explain the process and their decision making to you so that you have all the facts.
~ Lauren M.
Friendly, fast, and professional service at the highest quality. Really impressed with the results of their services, and my technician is very knowledgeable and helpful when I have any questions. They made sure I was fully educated on the services I received and perform check-ins to ensure my skin heals properly. Also, the most convenient location in Back Bay!
~ Jules B.
I cannot say enough great things about this SkinMD. The staff was amazing, and their services are amazing. I am so, so happy with how my nose came out, and I am now a lifetime customer of SkinMD and will be recommending SkinMD to everyone I know.
~ Carrigan D.
Meet YOU+
SkinMD providers review your full picture, symptoms, labs, health history, and goals before recommending any peptide protocol. Book a consultation to find out which treatment is right for you.
BOOK A CONSULTATION | (844) 754-6631
Frequently Asked Questions
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How do peptides support fat loss?
Growth hormone-stimulating peptides like Sermorelin directly enhance lipolysis, your body’s fat-burning pathway, while also improving body composition by preserving lean muscle. NAD+ supports the cellular metabolic efficiency that underpins fat burning.
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Do I still need to diet and exercise?
Yes. Peptides are medical optimization tools, not replacements for healthy habits. Most patients see the best results when peptide therapy is combined with appropriate nutrition and activity.
10 LOCATIONS ACROSS
THE GREATER BOSTON AREA
With ten locations across the greater Boston area, SkinMD is your local medspa. Find a SkinMD practice near you!
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